Curriculum Vitae 2017-09-07T08:59:24+00:00

MATTEO IANNACONE

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EDUCATION

  • 2011: Ph.D. in Molecular Medicine, Section of Basic and Applied Immunology, Universita’ Vita-Salute San Raffaele, Milan, Italy

  • 2007: Board Certification in Internal Medicine (summa cum laude), Università Vita-Salute San Raffaele, Milan, Italy

  • 2001: M.D. degree summa cum laude, University of Milan, Italy

POSITIONS AND TRAINING

  • 2015 – present: Head, Dynamics of Immune Responses, San Raffaele Scientific Institute, Milan, Italy

  • 2010 – 2015: Group Leader, Dynamics of Immune Responses, San Raffaele Scientific Institute, Milan, Italy

  • 2007 – 2010: Postdoctoral Fellow, Laboratory of Prof. Ulrich von Andrian, Harvard Medical School, Boston, MA

  • 2003 – 2007: Resident in Internal Medicine, San Raffaele Scientific Institute, Milan, Italy

  • 2001 – 2003: Postdoctoral Fellow, Laboratory of Prof. L.G. Guidotti and Prof. F.V. Chisari, The Scripps Research Institute, La Jolla, CA

HONORS AND AWARDS

  • 2017: Chiara D’Onofrio Award
  • 2016: European Research Council (ERC) Consolidator Grant

  • 2016: EMBO Young Investigator Award

  • 2015: European Association for the Study of the Liver (EASL) Young Investigator Award
  • 2011: European Research Council (ERC) Starting Grant

  • 2010: Armenise-Harvard Foundation Career Development Award
  • 2008: Armenise-Harvard Foundation Postdoctoral Fellowship

PROFESSIONAL ACTIVITIES

  • Journal Reviewer: Nature, Science, Nature Medicine, Immunity, Nature Immunology, Science Immunology, Proceedings of the National Academy of Sciences, Cell Host & Microbe, Cell Reports, Nature Communications, eLife, PLoS Pathogens, Hepatology, Journal of Hepatology, Gastroenterology, Journal of Immunology, Journal of Virology, Journal of Leukocyte Biology, European Journal of Immunology, Scientific Reports, Human Gene Therapy
  • Grant Reviewer: European Research Council (ERC), European Molecular Biology Organization (EMBO), Institut National de la Sante et de la Recherche Medicale (INSERM, Panel Member for the ATIP-AVENIR Program), Centre National de la Recherche Scientifique (CNRS), French National Research Agency (ANR), Austrian Science Fund (FWF), Swiss Cancer League, Agency for Science, Technology & Research (A*STAR) in Singapore, FINOVI Foundation, Dutch Digestive Foundation, Italian Ministry of Health, Italian Ministry of Research, Chilean Government Research Funding Agency (FONDECYT), Italian Multiple Sclerosis Foundation
  • Editorial Board: Frontiers in Immunology (Associate Editor), Current Opinion in Virology (Invited Section Editor)

  • Conference Organization: 1st International Workshop “Imaging the Immune System”, Milan, Italy (2014), 1st International Workshop “Viral Immunity”, Milan (2016), 2nd International Workshop “Imaging the Immune System”, Rehovot, Israel (2016), 1st EMBO Sectoral Meeting on Immunology, Bergamo, Italy (2017), 3rd EMBO Workshop “Imaging the Immune System”, Paris, France (2018), 2nd EMBO Sectoral Meeting on Immunology, Portugal (2018).

MAJOR ADMINISTRATIVE AND INSTITUTIONAL RESPONSIBILITIES

  • 2014 – present: Director, Intravital Imaging Facility, San Raffaele Scientific Institute, Milan, Italy

  • 2014 – present: Immunology Seminar Series Organizing Committee, San Raffaele Scientific Institute, Milan, Italy

  • 2015 – present: External Seminar Committee, San Raffaele Scientific Institute, Milan, Italy

TEACHING EXPERIENCE

  • 2012 – present: Adjunct Professor of Pathology and Immunology, Vita-Salute San Raffaele University, Milan, Italy

CONSULTANTSHIPS

  • Selecta Biosciences, Cambridge, MA

PATENTS

  • Immunonanotherapeutics that Provide IgG Humoral Response without T-Cell Antigen, United States Patent 8,906,381

  • Targeting of Antigen Presenting Cells with Immunonanotherapeutics, United States Patents 9,308,280

  • Adjuvant Incorporation in Immunonanotherapeutics, United States Patent 9,439,859

  • Nicotine Immunonanotherapeutics, United States Patent 8,932,595

  • Vaccine Nanotechnology, United States Patent 9,539,210

  • Vaccines Comprising Bisphosphonates and Methods of Use Thereof, United States Patent Application 20130309270

CURRENT FUNDING

  • European Research Council – Consolidator Grant (725038)

    FUNCTIONAL BIOLOGY OF HEPATIC CD8+ T CELLS
    €2,390,000
    Jul 2017 – Jun 2022
    Iannacone (Principal Investigator)

  • AIRC (Italian Association for Cancer Research) – Individual Grant MFAG (15350)

    THE ROLE OF ANTIGENIC STIMULATION IN THE PATHOGENESIS OF CHRONIC LYMPHOCYTIC LEUKEMIA
    €225,000
    Mar 2015 – Feb 2018
    Iannacone (Principal Investigator)

  • Italian Ministry of Health – Giovani Ricercatori (GR-2011-02347925)

    DISSECTING HBV PATHOGENESIS THROUGH THE USE OF INTRAVITAL MICROSCOPY
    €342,000
    Nov 2014 – Nov 2017
    Iannacone (Principal Investigator)

  • Fondazione Regionale per la Ricerca Biomedica (2015-0010)

    SINGLE-CELL ANALYSES OF LYMPHOCYTES THAT INFILTRATE AUTOIMMUNITY SITES: DISSECTING IMMUNOLOGICAL MECHANISMS OF RHEUMATOID ARTHRITIS
    €630,000
    2017 – 2020
    Iannacone (Co-Principal Investigator)

  • Funding from Gilead Sciences and GSK Vaccines

COMPLETED FUNDING

  • Armenise-Harvard Foundation – Career Development Award

    IN VIVO IMAGING OF ANTIVIRAL IMMUNE RESPONSES
    $1,000,000
    Nov 2010 – Oct 2015
    Iannacone (Principal Investigator)

  • AIRC (Italian Association for Cancer Research) – Program Project (9965)

    HARNESSING TUMOUR CELL/MICROENVIRONMENT CROSS TALK TO TREAT MATURE B-CELL TUMOURS
    €420,000
    Nov 2010 – Oct 2015
    Iannacone (Group Leader)

  • Armenise-Harvard Foundation – Senior Postdoctoral Fellowship

    ANTIVIRAL IMMUNE RESPONSES IN LYMPH NODES
    $180,000
    Apr 2008 – Apr 2010
    Iannacone (Principal Investigator)

  • Funding from Novartis Vaccines and Selecta Biosciences

SELECTED INVITED LECTURES

2017, Armenise lecture at the Italian Society for Biophysics and Molecular Biology (SIBBM) meeting, Milan, Italy
2017, British Society of Immunology Leukocyte Migration Affinity Group, Leeds, UK
2017, EMBO Symposium on Antigen Presentation, Salamanca, Spain
2017, XI Meeting of the Italian Immunological Society (SIICA), Bari, Italy
2017, CRC/SFB 900 Symposium in Hannover, Germany
2017, Centre d’Immunologie de Marseille-Luminy, France (host: Toby Lawrence)
2017, Laboratory of Molecular and Cellular Biology (LMCB), University College London, UK (host: Sophie Acton)
2017, Gotheborg University, Sweden (host: Susanna Cardell)
2016, Perspective in Vascular Biology (SFB 834), Frankfurt, Germany
2016, University of Bern, Switzerland (host: Jens Stein)
2016, Gordon Research Conference “Immunochemistry and Immunobiology”, Il Ciocco, Italy
2016, The Francis Crick Institute, London, UK (host: Caetano Reis e Sousa)
2016, Symposium on Immunity and Inflammation, CNIC, Madrid, Spain
2016, Pasteur Institute, Paris, France (host: Claude Leclerc)
2016, 8th International Singapore Symposium of Immunology, Singapore
2016, EMBO Young Investigator Meeting, Heidelberg, Germany
2016, Roche Glycart AG, Schlieren, Switzerland (host: Mario Perro)
2016, TIGEM, Naples, Italy (host: Carmine Settembre)
2016, University of Turin (host: Emilio Hirsch)
2016, Immunology Day, La Sapienza University, Rome, Italy
2015, GSK Vaccines, Siena, Italy (host: Ugo D’Oro)
2015, Trafficking of immune cells in inflammation, development and disease (SFB 914), Italy
2015, TRON, Mainz, Germany (hosts: Ugur Sahin)
2015, Karolinska Institute, Stockholm, Sweden (host: Eduardo Villablanca)
2015, University of Oxford, UK (host: Oliver Bannard)
2015, Cancer Research UK, London, UK (host: Facundo Batista)
2015, University College London, UK (host: Mala Maini)
2015, Istituto Nazionale Genetica Molecolare, Milano, Italy (host: Jens Geginat)
2015, University of Bern, Switzerland (host: Philippe Krebs)
2015, 1st European Chemokine and Cell Migration Conference, Villars-sur-Ollon, Switzerland
2015, European Society of Clinical Investigation Meeting, Cluj, Romania
2015, EASL International Liver Congress, Vienna, Austria
2015, University of Milan, Italy (host: Graziella Messina)
2015, Annual Meeting of the Swiss Society for Allergology and Immunology, Basel
2014, University of Freiburg, Germany (host: Robert Thimme)
2014, University of Essen, Germany (host: Karl Lang)
2014, Karolinska Institute, Stockholm, Sweden (host: Matti Sallberg)
2014, 3rd Conference on Translational Medicine on Pathogenesis and Therapy of Immune-mediated Diseases, Milan, Italy
2014, Vaccine and Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon (host: Klaus Frueh)
2014, Technical University in Munich, Germany (host: Percy Knolle)
2014, University of Calgary, Alberta, Canada (host: Paul Kubes)
2014, Vaccine Technology V, Playa Del Carmen, Mexico
2014, Symposium of the Research Unit 1202 “Determinants of elimination and persistence of hepatitis viruses”, Heidelberg, Germany
2014, 7th International Workshop “Bridging the gap”, Medical University of Vienna, Austria
2013, Institut Pasteur of Shanghai – Chinese Academy of Sciences, Shanghai, China (host: Jin Zhong)
2013, Spanish National Centre for Biotechnology (CNB), Madrid, Spain (host: Pablo Gastaminza)
2013, 15th International Congress of Immunology, Milan, Italy
2013, 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL), Singapore
2013, Keystone Symposium on Myeloid cells: Regulation and Inflammation, Keystone, Colorado, USA
2012, 43rd International Conference, Pio Manzu’ International Research Center, Rimini, Italy
2012, Novartis Vaccines and Diagnostic Research Center, Siena, Italy (host: Ennio De Gregorio)
2012, CeMM, Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria (host: Giulio Superti-Furga)
2012, Immunobiology of Microbial Host Interactions, 14th Annual Armenise-Harvard Foundation Symposium, Borgo San Luigi (Siena), Italy
2011, Ph.D. Student Retreat of the Institute for Research in Biomedicine, Bellinzona, Switzerland
2011, Department of Pathology and Immunology and W.H.O. Collaborating Centre for Vaccine Immunology, University of Geneva, Switzerland (host: Daniel Pinschewer)
2011, Trafficking of immune cells in inflammation, development and disease, Villa Vigoni (Menaggio), Italy
2011, Opening Plenary Symposium, Joint Meeting of the German (DGfI) and Italian (SIICA) Immunological Societies, Riccione, Italy
2011, The Weatherall Institute for Molecular Medicine, University of Oxford, UK (host: Enzo Cerundolo)
2011, Major Symposium on Innate Immunity, 98th Annual Meeting of the American Association of Immunologists, San Francisco, USA
2011, Institut Curie, Paris, France (host: Ana Maria Lennon-Dumenil)
2011, ICGEB Trieste, Italy (host: Federica Benvenuti)
2010, 11th International Symposium on Dendritic Cells in Fundamental and Clinical Immunology, Lugano, Switzerland
2010, University of Toledo, OH, USA (host: Isabel Novella)
2010, 4th International Symposium, Immunology Frontier Research Center, Osaka University, Japan
2010, Istituto Clinico Humanitas, Milan, Italy (host: Anna Villa)
2009, Immunochile – 9th Latin American Congress of Immunology, Vina del Mar, Chile